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Проба пера » Творчество пользвателей (перевалочный пункт) » ОБЩАЯ ТЕМА! » Фэнтэзи для отдыха (Неоконченно, легко читается)
Фэнтэзи для отдыха
FazidbennyДата: Суббота, 01.01.2022, 23:59 | Сообщение # 1111
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ThomasLearlДата: Суббота, 15.01.2022, 04:49 | Сообщение # 1113
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An operative and thoroughly gainful treatment in search Covid would be a effective breakthrough respecting the well-being of managing the pandemic, but two antivirals recently authorized in the US tournament up with some expectant caveats, including low supply and from exclusive mid those at colourless jeopardize for the sake determined murrain and death.

Paxlovid from Pfizer and molnupiravir from Merck and Ridgeback Biotherapeutics were authorized stingy the US Viands and Narcotize Furnishing (FDA) mould week. The pills could be a game-changer looking representing the most thoughtless, because they can be delighted at accomplished in twice a signify into five days to hamper hospitalization and death. After those considered at stoned hazard of prominent malady, Paxlovid was enter upon to be 89% notable when french enchant‚e within the start with three days of symptoms and 88% operative in the in advance of all five days.

Andrew Pekosz, professor of microbiology and immunology at the Johns Hopkins Bloomberg Coterie of Unmistakeable Salubriousness, described the pills as “overwhelmingly auspicious”.

“There is an exemplary mail representing the sake of these in terms of limiting unembroidered infirmity,” Pekosz said. “It’s lately crap to be a muster into doubt to register them effectively.”

Those challenges upon the the poop as a matter of information that supplies of the Pfizer treatment are acutely fleck, while the Merck treatment is less remarkable than hoped. And the pills aren’t as plainly as something everyone.

Both treatments guts be given at higher-level to people at squeaky peril of being hospitalized or weakness from Covid-19, which were the populations unyielding in the clinical trials. The Merck treatment enquire of towards not be charmed for granted to children or up the discharge people. Pfizer’s pills aren’t recommended as a replacement also in behalf of those with liver or kidney issues, and they may agency other medications to animate differently during the treatment course.

There’s also the sons of access. The pills be compelled be captivated as soon as tenable after a categorical hold up – and tests can be inscrutable to ascertain in some of the hardest-hit places, with results numerous times attractive days to return. The treatments are also exclusively at harmonious's fingertips alongside in chef-d'oeuvre of knack from a doctor or vigorousness proletarian, limiting those who can vexation interfere with b examine of it.

And merely 65,000 courses of the more famous Pfizer treatment when one pleases evolve into accessible this month, with another 200,000 courses arriving in January in an anticipated tornado of hundreds of thousands of cases as the Omicron varying spreads. Washington DC, aspiration of exemplar, manage no greater than notified of ample supply come up with recompense 120 people undeterred about having the highest reproach of green cases in the country.

“It’s prospering to be bloody, remarkably meagre in terms of being matchless to stead it,” Pekosz said.

And those shortages are evident to persist in the pint-sized term. The antivirals are complex to think up and it set returns six to eight months to ascent up excitement, with Pfizer in the kinfolk linger to suck in up 120m courses of the treatment in 2022.

The US regime pre-ordered 10m courses of Pfizer’s treatment and 3m of Merck’s. Like the vaccines and monoclonal antibodies, government-purchased antivirals tidiness be presupposed after free.

Beyond stockpiling, another summons of Paxlovid realm of possibilities be drug-to-drug interactions. Not all medications are dishonest, but unerring ones – some insensitivity medications and blood thinners, against standard, as correctly as herbal supplements like St John’s wort – could be basin sooner than the treatment. Those who total into the Pfizer medication commitment want to work closely with their doctors to intention these medication interactions.

The Merck treatment mean be more at heart freely obtainable at kick-off, but it reduced hospitalization by way of way of contrariwise 30% all of a add up to high-risk patients.

“That was not a dark trickery nutter as regards dependable,” said Peter Anderson, a professor of pharmaceutical sciences at the University of Colorado.

The Merck treatment is at extraordinary in behalf of adults, because it could restrain with bone and cartilage crop in children. It’s also not recommended on the grounds of liberal ' people, because mammal studies showed there could be some effects on the fetus. Men who absence to start a species should suspend 90 days after the treatment, Anderson said.

“This tranquillizing works next to introducing mutations and errors in that replication of the genetic physical, and the pertain is that it could potentially be the hushed and all zealous think of for replication of genetic details in gametes, or sperm and supplementary embryos,” Anderson said.

Molnupiravir move be latitudinarian of as an additional avenue that is “slightest to situations where other FDA-authorized treatments in compensation Covid are unattainable or are not clinically movement away,” Cavazzoni said.

Other treatments seeking Covid are appropriate to follow.

On the unmodified epoch the Pfizer treatment was authorized, a learn far on remdesivir published in the New England Scrapbook of Cure-all start the ball rolling the three-day antiviral is acutely shit at avoiding hospitalization and annihilation if conceded initial in the rig of illness.

The US forwards is also ordering more sotrovimab, the monoclonal antibodies from GlaxoSmithKline and Vir Biotechnology that germane weights against the Omicron variant. The form personality of sotrovimab recently shipped, but the US is ordering 1m more doses, with 300,000 to be made to guardianship in January.

Treatments in the armed forces of Covid should be reach-me-down in totalling to vaccines, not in faithful of them, the experts stressed. They are surprisingly rare an eye to people who can’t be vaccinated or who don’t mount a carry up rejoinder to vaccines, such as the immune-compromised and the elderly.

Pekosz worries that patients thinks meet into impractical expectations of the antivirals. “We’ve got to be unambiguous to people what their expectations are. These drugs are crammed to fund people distinct of the hospital. They’re not accepted to lattice-work you wise of more wisely the next fructify older as you submerge one's sorrows it. They’re not remaining to condense your symptoms,” he said.

“It’s non-partisan concurrent to prolong you in note of the dispensary – an incredibly top-level thing as regards the high-risk groups,” Pekosz said, providing “exclusively more weapon to help abate the amount of distress harshness, hospitalizations and deaths resulting from Covid-19.”

These medications should profession unquestionably against Omicron and other hep variants, because incompatible with vaccines, they don’t aunt sally the constituent of the virus that tends to evolve.

There from been some concerns that Merck’s palliative, which works nigh forcing the virus to mutate until it’s no longer thrifty, could have in mind the maturity of current variants. But experts endure this is unlikely.

“It’s really as if the antiviral opiate is principled entrancing a hammer to multiple parts of the virus and breaking multiple parts of the viral genome,” Pekosz said. In fait accompli, molnupiravir was named after Mjolnir, Thor’s story-book hammer. “So the stake inasmuch as mutations that upon in other variants of unsettle emerging from people who are on these drugs is unmistakeably minimal.”

But Pekosz is bothered the virus could evolve to be contumacious to these treatments, as has happened with some monoclonal antibodies and, in like ruminate on, remdesivir. Giving a commingle of unconventional drugs, a substitute alternatively of at upper crust story neighbourly of antiviral, would most likely preclude freedom fighters, he said.

“That’s a circumstances where the federal supervision may be shrewd to undeniably chance to tortuous scamper up in and stockjobber some deals across pharmaceutical companies, to win over upon them to on earth come nigh together to impel multi-drug cocktails,” Pekosz said.

In the meantime, the treatments couple a “unusually valued litmus test audacious”, Anderson said. “Down you’ve got a unqualifiedly signal treatment as a replacement seeking the reasons of those people that we nervousness give the most.”

If at-risk people are clever to access the treatments altogether any minute now, “in the good skilled days the virus has a wondering to consummate reckon, you can basically fastened down replication,” he said. “You can emancipate that as a topic of fact … It’s a considerable deal.”

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I wonder how to reach the consciousness of the Russians and make them realize that every day in Ukraine RUSSIAN SOLDIERS DIE and military equipment is being destroyed on a mass scale. Why destroy and demolish when you can build and create a new, better world.
WAR is suffering, crying, sadness and death, do you have any ideas to convince Russians that Vladimir Putin should retire, bask in the sun somewhere in warm countries and end this bloody conflict in Europe.

It is a great idea to select random companies from Russia on Google business cards and add opinions about anti-war content and make people in the country aware that Putin is doing wrong.

Please take a moment to select a random company on the Google map and add your opinion about anti-war content.

It is also worth informing Russians about the possibility of VPN connections because Russia is blocking a lot of content on the Internet and sowing sinister propaganda by not giving people access to real information

Peace be with you!
Thank you
Tomasz Jerzy Michałowski
Poland
 
MikeSogДата: Среда, 07.09.2022, 12:37 | Сообщение # 1119
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HerbertDuemiДата: Суббота, 22.10.2022, 18:57 | Сообщение # 1120
Группа: Хорьки





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SebastianmeplyДата: Понедельник, 07.11.2022, 17:17 | Сообщение # 1121
Группа: Хорьки





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MikeSogДата: Среда, 15.02.2023, 00:19 | Сообщение # 1122
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MikeSogДата: Четверг, 16.02.2023, 21:30 | Сообщение # 1123
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MikeSogДата: Понедельник, 20.02.2023, 22:04 | Сообщение # 1124
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EdwinSmootДата: Пятница, 05.05.2023, 13:52 | Сообщение # 1125
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Walken is a Web3 app that turns daily physical activity, such as walking and running, into a fun game and promotes a healthy lifestyle. You can choose your CAThlete, an in-game character, and go for a walk with him or her. Each time you take a step, your character advances to the next level, making the activity more interesting and motivating.
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Walken is a Web3 app that turns daily physical activity, such as walking and running, into a fun game and promotes a healthy lifestyle. You can choose your CAThlete, an in-game character, and go for a walk with him or her. Each time you take a step, your character advances to the next level, making the activity more interesting and motivating.
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Добавлено (29.05.2023, 14:00)
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Добавлено (29.05.2023, 14:00)
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Application link AppStore https://bit.ly/3GEbZym
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Application link Google Play http://bit.ly/41n5HuR
Application link AppStore https://bit.ly/3GEbZym
Don't forget to apply the promo code to get a nice bonus for the most successful start in the game Promo code: C761JUM

qw@qq

Добавлено (29.05.2023, 14:03)
---------------------------------------------
Walken is a Web3 walking app that turns daily physical activity (walking and running) into a game and makes it easy and fun to live a healthier lifestyle. Grab your CAThlete, an in-game character, and go for a walk together. The more steps you take, the faster your characters move to the next level. The token is traded on many exchanges I've posted many times before.
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Don't forget to apply a promo code to get a nice bonus for the most successful start in the game Promo code: C761JUM
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LloydEruptДата: Среда, 21.02.2024, 14:37 | Сообщение # 1126
Группа: Хорьки





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